🎞 Video: the new challenges of CAR-T cells

Published on 27 October 2022

CAR-T cells are a new type of therapy that offers high hopes for cancer fighting. With this video, the SiRIC CURAMUS, the film director Cyprien Bisot and Dr Françoise Norol guide you through the functioning of this immunotherapy and its method of production with a passage in the Service of Clinical Hematology of Pitié-Salpêtrière and in the Novartis Cell For Cure production center.

👉 Find the video below:

📌 In addition, find the long version of this video which includes a description of the prospects for improving the effectiveness of these treatments:

📖 Project « Trials of Damocles » publication

Published on 26 October 2022

In 2019, a SiRIC CURAMUS interdisciplinary team led by Marie-Pierre Dann, specialised clinical nurse (Hematology Department of the Pitié-Salpêtrière Hospital) won the Force Hemato award with « Trials of Damocles ». This research project aims better to understand the needs, expectations and experiences of patients diagnosed with chronic lymphocytic leukemia (CLL), stage A. About half of these patients, under active surveillance and often asymptomatic, may not ever need treatment. This short paper aims to present the context and the interrogations of this research project as well as to explain how the humanities and social sciences, and more particularly philosophy, may bring a pertinent and precious outlook on such a topic.

👉 Find the publication here

📢 INCa general public conference “Live and work with a cancer”

Published on 25 October 2022

As part of the “Cancer and Employment” meetings, the French National Cancer Institute organizes on the 22th November 2022 a general public conference “Live and work with a cancer” to discuss and exchange about the maintain and return to employement of people affected by a cancer.

📌 Place: Cité des sciences et de l’industrie, Paris

👉 Registrations: https://rencontresinca-cancertravail.fr/inscription/

👉 Pre-program: https://rencontresinca-cancertravail.fr/programme/

11th International Workshop on Waldenström’s Macroglobulinemia

Published on 24 October 2022

From 27th to 30th October 2022 will be held in Madrid the 11th International Workshop on Walendström’s Macroglobulinemia (WM), one of the diseases studied in CURAMUS in the program 2 “Rare immuno-haematological cancers”.

Pr Véronique Leblond will co-chair the session “Chemoimmunotherapy” in which she will make a présentation “FILO Bendamustine Rituximab Study”, and will have a talk on “Obinutuzumab and Idelalisib in WM” in the session “Novel Treatment Approaches to WM-Clinical I”. Moreover, Dr Damien Roos-Weil will present “Integration of cytogenetic and molecular screening for first line patients” in the session “WM Genomics I” and “DNA Methylation Profiling in WM” in the session “WM Genomics II”.

👉 Full program: http://www.waldenstromsworkshop.org/index.php/scientific-program

👉 Registrations: http://www.waldenstromsworkshop.org/index.php/registration

The P3S Platform invites you to its experience feedback seminar

Published on 24 October 2022

The Post-Genomic platform of Pitié-Salpêtrière (P3S) organizes a seminar on experience feedback thursday 10th November 2022 from 10 to 12 am, room 115, 91 boulevard de l’Hôpital.

📌Find the program below:

10h00 : Presentation of the P3S proposed applications on genomic and proteomic

10h20 : Pierre-Yves Boëlle (Cinbios, UMS PASS)
Presentation of the UMS bioinformatic pole

10h30 : Franck Bielle (U1127, ICM, Institut du cerveau et de la moëlle)
Application of the méthylome to brain tumors classification

10h50 : Sylvie Briquet (U1135, CIMI, Centre d’Immunologie et des Maladies Infectieuses)
Genetic modifications in Plasmodium and genome analysis by long read sequencing.

11h10 : Elise Balse/Camille Blandin (U1166, UMR ICAN, Maladies cardiovasculaires et métaboliques)
Application of proteomic analysis to the study of the role of a scaffold protein in the cardiomyocyte

11h30 : Emmanuel Laplantine (U944, GenCellDis, Génomes, biologie cellulaire et thérapeutique, Hôpital Saint-Louis)
Mutations of the OTULINE deubiquitinase predispose to staphylococcus infections in human: proteomic analysis of the linear ubiquitination in patients-derived fibroblasts

📌 3rd national OncoNeuroTox scientific day

Published on 13 October 2022

With the support of SiRIC CURAMUS, the OncoNeuroTox network, dedicated to the management of neurological consequences of anti-cancer treatments, organizes its 3rd national scientific day on wednesday 23 november 2022 in Paris. The interventions will discuss neurotoxicities of conventional, targeted and immunotherapies treatments.

👉 Registrations: https://my.weezevent.com/journee-onconeurotox-2022

👉 Place (remote format proposed): Institut du Cerveau, Hôpital Pitié-Salpêtrière, 47 boulevard de l’Hôpital, 75013 Paris

👉 Program:

🎞 Video: in the heart of MSI tumors

Published on 13 October 2022

MSI tumors (for Microsatellites Instability) are a type of tumors with genomic alterations due to a defect in the DNA repair system. To better understand the origin of these cancers and the consequences of their genomic features, especially on anti-tumor treatments, SiRIC Curamus, MSI and Cancer research team at the Saint-Antoine Research Center and the film director Cyprien Bisot present this popularized video 👇

📽 CURAMUS will have its cinema for the Fête de la Science 2022 !

Published on 12 October 2022

For this new 2022 edition, CURAMUS will be present at the “Fête de la Science” organized by Sorbonne Université ! Middle and high school students will have the possibility to attend the screening of our 2 vidéos “In the heart of MSI tumors” and “The new challenges of CAR-T cells”, and participate to numerous workshops dedicated to various themes and set up in the different sites of Sorbonne Université throughout the event.

📌 Date of CURAMUS videos screeening: 13th october 2022

📌 Place: Faculty of Medicine, 105 boulevard de l’Hôpital, 75013 PARIS

The French National Cancer Institute renews its Health Democracy Committee

Published on 4 October 2022

Call for applications for the renewal of the Health Democracy Committee from the French National Cancer Institute

The Health Democracy Committee is a permanent consultation body whose obective is to bring the experience and expertise of users of the heath system and health professionals essential to improve the quality and relevance of the strategy and actions of the institute. Place for sharing and reflection, this committee is closely associated with the Institute’s landmark works. If you would like to join the Heath Democracy Committee, do not hesitate to apply ! You can also relay this call for applications if you know people who might be interested.

📌 Fore more information on the Committee and its working methods, you can contact Marie-Sophie Gannac, head of the Health Democracy mission msgannac@institutcancer.fr tél. 01 41 10 15 84.

👉 To apply: https://bit.ly/39J315N.

Curamus was present at the “Applied Human Factors and Ergonomics” congress

Published on 31 August 2022

Within the framework of the 13th international conference “Applied Human Factors and Ergonomics”, which took place from the 24th to the 28th July 2022 in New-York, Pr Karine Berthelot-Guiet and Dr Juliette Charbonneaux had the opportunity to present work carried out within Curamus and entitled “Rare cancers and digital quest for authority during COVID 19 pandemic“, through a session “Human Factors in Disease Control and COVID-19 Pandemic Prevention” for which they were co-chairs.

👉 Find the program of the conference here.